What is the stated limit of quantification?

• A. 855 mm^2
• B. 0.00785 mm^2
• C. 385 mm^2
• D. 1000 mm^2

Answer: (C)

The limit of quantification is the smallest amount that can be measured with acceptable precision and accuracy in a given method. When quantification is tied to an area measurement, LOQ is the minimum area that stays within the validated, linear range and meets the method’s quality criteria. Here, the LOQ is 385 mm^2, meaning measurements at or above this area can be quantified reliably, while smaller areas fall outside the validated quantifiable range. The other values do not reflect the validated quantifiable range for this method.